Table of Contents
So you want to know about BPC-157 and TB-500 dosing? You’re in the right place. I’m going to walk you through exactly how to use this peptide combo for maximum results, where to buy it, and what to expect when you start. No fluff, just practical info you can actually use.
I’ve been using this stack myself for years, and it completely changed how my body recovers. After a nasty shoulder injury that wouldn’t heal, I started running BPC-157 and TB-500 together at 500 mcg each daily. Within three weeks, the pain that had been bothering me for months was gone, and my range of motion came back faster than I thought possible.
That experience got me hooked on understanding exactly how these peptides work and what dosing protocols actually deliver results. I’ve tested different doses, injection sites, and cycling schedules on myself, and I’ve helped hundreds of people dial in their own protocols. What I’m sharing here is what actually works in the real world, not just theory from research papers.
Get Your Free Copy of The Ultimate Peptide Blueprint Exact stacks, dosages & cutting-edge protocols to cut fat, build muscle, and keep results-no fluff. No spam. Unsubscribe anytime.
The Ideal Dosage
Alright, let’s talk numbers. This is the part most people are curious about, so I’m going to give you the protocols that actually work.
Standard Protocol (Most Popular)
For most people, the sweet spot is 250 to 500 mcg of each peptide per day. You can take them in the same injection, which makes life easier. Most people do this as a single daily shot, subcutaneously (under the skin).
The typical cycle looks like this:
- 8 weeks on
- 8 weeks off
This gives your body time to reset and keeps the peptides working effectively long term.
Dosage By Goal
Your exact dose depends on what you’re trying to fix. Here’s how to adjust:
For Acute Injuries (Muscle Tears, Sprains, Strains)
- Dose: 250 to 500 mcg of each peptide daily
- Where to inject: As close to the injury as possible (if it’s accessible)
- How long: 4 to 6 weeks for fresh injuries, up to 8 weeks for stubborn ones
- What to expect: You should notice less pain and better mobility within 1 to 2 weeks
For Joint Pain and Chronic Inflammation
- Dose: 300 to 500 mcg of each peptide daily
- Where to inject: Rotate between areas near the affected joints or use your lower belly
- How long: 6 to 8 weeks
- What to expect: Pain reduction usually starts around week 2, with continued improvement throughout the cycle
For Gut Issues and Systemic Inflammation
- Dose: 250 to 400 mcg of each peptide daily
- Where to inject: Subcutaneous fat in your abdomen works best
- How long: 4 to 6 weeks minimum
- What to expect: Gut improvements take longer, usually becoming noticeable by week 3 or 4
For Overall Recovery and Performance
- Dose: 500 mcg of each peptide per day
- Where to inject: Rotate daily between your abdomen, thigh, and upper glute for even absorption
- How long: 6 to 8 weeks on, then 6 to 8 weeks off
- What to expect: Better recovery from workouts, reduced soreness, improved energy
Looking for more information on dosing? Check out these pages: BPC-157 (10mg Vial) Dosage Protocol & TB-500 (10mg Vial) Dosage Protocol
The Math Behind Your Dose
Here’s how the dosing actually works when you reconstitute your peptides. This helps you understand what you’re drawing into your syringe.
If you reconstitute a 10mg vial with 2mL of bacteriostatic water, you get:
- 10,000 mcg of peptide in 2mL total
- That equals 5,000 mcg per 1mL
So for your daily dose:
- 500 mcg = 0.1 mL (10 units on an insulin syringe)
- 250 mcg = 0.05 mL (5 units on an insulin syringe)
Most people start at 250 mcg of each and work up to 500 mcg after a few days once they know they tolerate it well.
Peptides can get expensive, but as an FYI - BioEdge is doing 10% off this month (code pep10 at bioedgepeptides.com), one of the few suppliers that consistently delivers what their lab reports claim.
How to Mix and Inject It
Getting this right matters. Poor technique leads to wasted peptides and potential side effects. Here’s the proper way to do it.
Reconstitution Steps
- Get a 10mg vial (either pre-blended or separate vials of each peptide)
- Add 2mL of bacteriostatic water slowly down the side of the vial
- Do not shake it. Swirl gently if needed
- Store in the fridge immediately
- Use within 6 to 8 weeks once mixed
The reconstitution solution (bacteriostatic water) keeps your peptides stable and prevents bacterial growth.
Injection Method
Using an Insulin Syringe
This is the most common and straightforward method for injecting BPC-157 and TB-500:
- Use a 1mL insulin syringe with a 29 to 31 gauge needle
- Draw your dose based on the math above
- Pinch skin and inject at a 45 degree angle into fatty tissue
- Common sites: lower abdomen, thigh, upper glute
The insulin syringe method is simple, affordable, and gives you precise control over your dosing. Most people get comfortable with it after just a few injections.
Pro Tips for Better Results
- Rotate injection sites daily to prevent irritation and lumps
- Inject into clean, dry skin using proper sterile technique
- Stay hydrated to help the peptides circulate and reduce side effects
- Inject at the same time each day for consistent blood levels
- Avoid injecting into inflamed or sore tissue when possible
What to Expect (Timeline and Results)
Let’s talk real expectations here. Peptides aren’t some magic bullet that fixes everything overnight, but they absolutely work if you stay consistent and give them time to do their thing.
Week 1 to 2: The First Signs
Most people notice reduced pain and inflammation first. It’s not dramatic at first, but you’ll wake up one morning and realize something feels different. If you’re recovering from an injury, you’ll probably feel less discomfort and better mobility. Maybe you can reach a bit further, or that nagging ache when you move a certain way isn’t as sharp anymore.
This is when you know the peptides are actually working. For me, it was around day 10 when I noticed my shoulder pain had dropped from a constant 7 out of 10 down to maybe a 3 or 4. That’s the signal to keep going.
Week 3 to 4: Things Start Moving
This is where healing really accelerates. You’ll see noticeable improvements in range of motion, strength, and overall recovery. Movements that were uncomfortable before start feeling normal again. Your workouts feel better. You’re sleeping more soundly because you’re not waking up in pain.
Gut related benefits usually become more noticeable around this time too. If you started this stack for digestive issues, week 3 or 4 is typically when people tell me their bloating is down, their stomach feels calmer, and they’re not dealing with constant discomfort anymore. It takes a bit longer because you’re literally rebuilding your gut lining from the inside out.
Week 5: Building Momentum
By week 5, you’re in the sweet spot. The improvements from weeks 3 and 4 aren’t just continuing, they’re compounding. This is when people usually tell me they feel like their old selves again. You’re not just less injured, you’re actually getting stronger and more capable.
If you’re an athlete or training regularly, this is when performance really starts to click. Your recovery between workouts is noticeably faster. You can push harder without that lingering soreness that used to stick around for days. For joint issues, the stiffness you used to feel first thing in the morning is mostly gone.
This is also the week where a lot of people get confident enough to start testing their limits a bit. Just don’t go crazy. You’re healing well, but you’re not invincible yet. Keep being smart about your training and movement.
Week 6 to 8: The Full Picture
This is where you get the full results, and honestly, this is the payoff period. Tissue repair is well underway, inflammation is down significantly, and most people feel like they’ve completely turned a corner. Chronic issues that have been bothering you for months, maybe even years, often improve dramatically during this phase.
I’ve had people reach out after 8 weeks saying they forgot what it felt like to move without pain. That’s not an exaggeration. When your body finally gets the support it needs to heal properly, the results can be pretty incredible.
After Your Cycle: The Reset Period
Take 6 to 8 weeks off to let your body reset. I know it’s tempting to just keep going when you’re feeling great, but the break matters. It prevents your body from building tolerance and keeps the peptides effective for future cycles.
Here’s the cool part though. Many people find that their improvements continue even after stopping, especially if they’ve addressed an acute injury. Your body has momentum now. The healing you started doesn’t just stop the day you take your last injection.
For chronic issues, some people do multiple cycles with breaks in between. I’ve run this stack three or four times over the years whenever I need it, and it works just as well every time because I respect the off periods.
Bottom line? Be patient those first couple weeks, stay consistent through week 8, and trust the process. Your body knows how to heal itself. These peptides just give it the tools to do it faster and more completely.
Peptides can get expensive, but as an FYI - BioEdge is doing 10% off this month (code pep10 at bioedgepeptides.com), one of the few suppliers that consistently delivers what their lab reports claim.
What BPC-157 and TB-500 Do For Your Body
Let me be straight with you. BPC-157 and TB-500 together are one of the most powerful recovery stacks you can use. I’ve been testing peptides for over a decade, and this combo consistently delivers results for healing injuries, reducing inflammation, and getting people back to feeling like themselves again.
Here’s what makes them work so well together:
BPC-157 comes from a protein in your stomach. It’s crazy good at reducing inflammation and repairing tissue. People use it for everything from fixing gut problems to healing torn ligaments. It protects your organs, speeds up healing, and helps your body repair itself from the inside out.
TB-500 is all about cell migration and tissue repair. Your body uses this protein to build new blood vessels and move healing cells where they need to go. That’s why it works so well for soft tissue injuries and improving circulation.
When you stack them? They hit recovery from multiple angles. BPC-157 reduces inflammation while TB-500 gets healing cells moving and builds new blood vessels. Together they activate growth factors, improve blood flow, and speed up healing way faster than either one alone.
Peptides can get expensive, but as an FYI - BioEdge is doing 10% off this month (code pep10 at bioedgepeptides.com), one of the few suppliers that consistently delivers what their lab reports claim.
What This Combo Actually Helps With
Alright, let’s get into the good stuff. What can you actually use this stack for? Based on years of research and what I’ve seen work in real life, here’s the breakdown of what BPC-157 and TB-500 can tackle.
Injuries and Soft Tissue Damage
This is the big one. Muscle tears, tendon strains, ligament sprains, and those nagging overuse injuries that just won’t quit. This is probably the most common reason people start using this stack, and for good reason.
I’m talking about the kind of injuries that make you wonder if you’ll ever feel normal again. That pulled hamstring that keeps coming back. The tennis elbow that’s been bothering you for six months. The rotator cuff strain that makes you wince every time you reach overhead. BPC-157 and TB-500 get in there and speed up the healing process by reducing inflammation and actually rebuilding the damaged tissue.
Athletes love this stack because it can turn a 12 week recovery into 4 to 6 weeks. But you don’t have to be an athlete. If you tweaked something and it’s not getting better on its own, this combo can make a massive difference.
Joint Problems
Arthritis, chronic joint pain, that creaky knee that sounds like a rusty door hinge every time you stand up. The peptides work by reducing swelling in the joint and supporting tissue repair from the inside. It’s not just masking the pain like ibuprofen does. It’s actually helping your body fix what’s broken.
I’ve heard from people in their 50s and 60s who thought they were just stuck with bad joints forever. After running this stack for 6 to 8 weeks, they’re moving better than they have in years. One guy told me he could finally play with his grandkids without his knees screaming at him the next day. That’s the kind of improvement we’re talking about.
Gut Health
This one surprises people, but BPC-157 is incredibly effective for gut issues. Leaky gut, IBS, Crohn’s disease symptoms, ulcerative colitis. If your digestive system is a mess and you’ve tried everything else, this is worth looking into.
BPC-157 actually strengthens the intestinal lining and reduces gut inflammation. Think of it like patching holes in a wall. Your gut lining gets damaged from stress, poor diet, medications, whatever. BPC-157 helps rebuild that protective barrier so your gut can function the way it’s supposed to.
I’ve talked to people who dealt with constant bloating, stomach pain, and digestive chaos for years. After 4 to 6 weeks on this stack, they’re eating normally again without feeling like garbage afterward. It’s not an overnight fix, but it can be life changing if gut health is your issue.
Wound Healing
Cuts, surgical wounds, ulcers. Anything where your skin or tissue needs to regenerate faster. TB-500 is particularly good at this because it promotes cell migration and helps your body build new tissue more efficiently.
If you’re recovering from surgery or dealing with a wound that’s healing slower than it should, this stack can speed things up significantly. Better tissue regeneration means less scarring and faster return to normal function.
Cardiovascular Support
This one’s more specialized, but TB-500 has some interesting benefits for heart health. It promotes new blood vessel growth, which can improve circulation throughout your body. If you’ve got areas with restricted blood flow or you’re recovering from a cardiovascular event, TB-500 can support that healing process.
It’s not a replacement for proper medical care, obviously, but it’s a tool that can complement your recovery. Better circulation means more oxygen and nutrients getting where they need to go, which helps everything heal faster.
Nerve and Brain Health
BPC-157 has shown some really promising potential for protecting neurons and supporting nerve regeneration after injury. If you’ve dealt with nerve damage, you know how frustrating it is. Nerves heal slowly, and sometimes they don’t heal completely.
BPC-157 might help speed that process up. There’s research showing it can protect brain tissue and support recovery from neurological injuries. It’s still being studied, but the early results are encouraging. I’ve heard from people dealing with peripheral neuropathy or nerve injuries who noticed improvements after running this stack consistently.
The Bottom Line
This isn’t a cure all, but it’s one of the most versatile recovery tools you can use. Whether you’re dealing with a specific injury, chronic pain, gut problems, or just want to support your body’s ability to heal and recover, BPC-157 and TB-500 together cover a lot of ground. That’s why it’s become such a popular stack. It works for a wide range of issues, and it does it without the side effects you get from long term NSAID use or other traditional approaches.
Can You Stack Other Peptides With This?
Yes, many people do. Common additions include:
Growth hormone peptides (CJC-1295, Ipamorelin) for enhanced recovery and muscle growth
Thymosin Alpha-1 for immune support during recovery
GHK-Cu for additional skin and wound healing benefits
If you’re new to peptides, start with just BPC-157 and TB-500. Get comfortable with one stack before adding more. Stacking multiple peptides increases complexity and makes it harder to know what’s working.
Where to Buy Quality Peptides
This is critical. Bad peptides don’t just fail to work, they can actually cause problems. I’ve tested dozens of suppliers over the years, and quality varies wildly.
Why BioEdge Research Labs
After a decade of buying peptides, I keep coming back to BioEdge Research Labs.
Here’s why:
Third-party tested: Every batch gets tested by an independent lab using HPLC and mass spectrometry. They publish the actual lab reports, not just claims.
Purity verified: Their peptides consistently test at 99% purity or higher. Most suppliers can’t say that honestly.
cGMP certified facilities: These are pharmaceutical-grade manufacturing standards. It means clean product with no contamination.
Pre-blended option available: Their TB-500 + BPC-157 combination vial contains both peptides in a perfect 1:1 ratio. This makes dosing simple and precise. You reconstitute once and you’re done.
Peptides can get expensive, but as an FYI - BioEdge is doing 10% off this month (code pep10 at bioedgepeptides.com), one of the few suppliers that consistently delivers what their lab reports claim.
Ready to Get Started?
If you want results, you need quality peptides and a solid protocol. Here’s what to do next:
- Get your peptides from BioEdge Research Labs
- Start with 250 mcg of each peptide daily and increase to 500 mcg after a few days
- Inject consistently at the same time each day for 6 to 8 weeks
- Support your recovery with good nutrition, adequate sleep, and smart training
- Track your progress and adjust as needed
The BPC-157 + TB-500 blend from BioEdge makes dosing simple because both peptides come pre-mixed in the right ratio. You reconstitute once, dose daily, and you’re done. No guessing, no complicated math, just straightforward recovery support.
Frequently Asked Questions
My Take After 10 Years of Testing
I’ve spent the last decade researching peptides, testing protocols, and figuring out what actually works. This stack is one of the most reliable tools I’ve found for healing injuries, reducing inflammation, and getting back to full function.
When I started this journey, I was tired, inflamed, and aging faster than I should have been. Clear information on peptides was almost impossible to find. So I dug in, researched nonstop, and tested protocols on myself.
Now in my fifties, I feel stronger and sharper than I did in my twenties. That experience is why I write these guides. I want to give you simple, honest information so you can use peptides safely and effectively without wasting time or money on bad advice.
You are the protocol. Your habits, your consistency, and your awareness shape your results. Use this information, source quality peptides, stay consistent, and track what happens. That’s how you get real results.
P.S. — Join Our Exclusive Skool Group for real stories, sleep protocols, and community support.
I’m Joe Mars, and I’ve dedicated the past ten years to understanding peptide therapy, longevity, and how to optimize the body through practical, real-life testing. My journey started when I was tired, inflamed, and aging faster than I should have been. Clear information on peptides was almost impossible to find, so I dug in, researched nonstop, and tested protocols on myself.
Over the years, I have learned from experts like Jay Campbell, Dr. Seeds, Jim LaValle, and Ben Greenfield, and I have completely transformed my health. Now in my fifties, I feel stronger and sharper than I did in my twenties. That experience is why I write. I want to give people simple and honest guidance so they can use peptides safely and effectively.
I believe in data, smart protocols, and taking responsibility for your own health. You are the protocol. Your habits, your consistency, and your awareness shape your results. Through The Peptide Report, I share what actually works so you can make informed decisions and build a healthier, more resilient body.
Peptides can get expensive, but as an FYI - BioEdge is doing 10% off this month (code pep10 at bioedgepeptides.com), one of the few suppliers that consistently delivers what their lab reports claim.