Paradigm Peptides Review: Quality and Efficacy of Peptides and SARMs

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Paradigm Peptides Review: Quality and Efficacy of Their Peptides and SARMs

Paradigm Peptides shut down - owner Matthew Kawa guilty plea federal case December 2025 sentencing March 2026

I’m going to save you some time. If you came here looking for a Paradigm Peptides review because you’re thinking about ordering from them, you can’t. They’re gone.

Paradigm Peptides was shut down after a federal investigation found that products they labeled as SARMs actually contained testosterone, a controlled substance. The owner, Matthew Kawa, pled guilty to federal charges in December 2025. His sentencing is scheduled for March 2026.

But this article still matters. Because the questions people were asking about Paradigm — about product quality, testing, and whether you can trust what’s on the label — are the exact questions you should be asking about any peptide or SARM supplier. And the Paradigm case proves exactly why.

I’ve been in this space for over 10 years. Let me walk you through what Paradigm got wrong, what to look for in a supplier you can actually trust, and where to get the products you’re looking for now.

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What Paradigm Peptides Used to Sell

Paradigm carried a wide product line. Peptides, SARMs, PCT supplements, nootropics, and CBD products. Some of their most popular offerings included Ostarine (MK-2866), LGD-4033, RAD-140, MK-677, YK-11, SR9009, and GW-501516.

On the surface, it looked like a solid operation. Professional website. Third-party testing claims. Detailed dosage recommendations. Good customer reviews on Trustpilot and Reddit. They accepted major credit cards, offered international shipping through UPS, and had a money-back guarantee.

All the right boxes were checked. And none of it mattered.

Because federal investigators determined that many of the products advertised and sold as SARMs contained testosterone instead. Thousands of customers across the United States received products that didn’t match their labels. People making decisions about what to put in their bodies based on a label that was lying to them.

That’s the core issue here. It doesn’t matter how good the website looks or how many payment options they offer if the product in the vial isn’t what they say it is.

The Quality Control Problem

Paradigm marketed themselves hard on quality. They talked about lab testing, HPLC analysis, third-party verification, and detailed lab reports. Their 2023 lab testing results were supposed to be a stamp of credibility.

And yet, the products still contained the wrong compound.

This is important for every peptide buyer to understand. Claims of testing mean nothing without verification you can actually trust. A company can say “third-party tested” all day long. They can put a certificate of analysis on their website. But unless those results come from a genuinely independent lab, and unless the testing is done on every batch rather than a single sample from two years ago, you have no real assurance of what you’re getting.

The Paradigm case should change how you evaluate every supplier going forward. Don’t take their word for it. Look at who’s doing the testing. Look at whether results are batch-specific. And if a company gets defensive when you ask for documentation, that tells you everything you need to know.

The “Research Only” Disclaimer Doesn’t Protect Anyone

Paradigm, like most peptide and SARM suppliers, put “research purposes only” disclaimers all over their site. Their employee even told a reporter from The Markup that they sell “under a research umbrella” while simultaneously admitting the market is really for human use.

That disclaimer has never held up in court. Federal prosecutors have successfully argued in multiple cases that when companies advertise to bodybuilders, provide dosage recommendations, and sell products clearly intended for human consumption, the “research only” label is just a disguise.

I’m telling you this not to scare you but to make sure you understand the landscape. The companies that survive long-term in this industry are the ones that operate with integrity from the ground up. Not the ones hiding behind disclaimers while cutting corners on what’s actually in the product.

Where to Get These Products Now

If you were buying peptides from Paradigm and need a new source, here’s where I’d point you.

I’ve been working with BioEdge Research Labs for years, and they’re who I recommend to everyone in our community. Here’s why they’re a fundamentally different operation than what Paradigm was running:

Every batch is independently tested. Not a sample from six months ago. Every batch. The testing covers purity, identity, and potency from an independent U.S. lab.

Cold-chain shipping. Peptides break down in heat. BioEdge ships with temperature control so you get the product at full potency. This is a basic requirement that too many suppliers ignore.

Consistent results. I’ve ordered from them enough times to know the quality doesn’t fluctuate. That consistency is what lets you build a reliable protocol.

Use code PEP10 for 10% off your order.

One thing I need to mention: Make sure you’re on the real BioEdge site at bioedgeresearchlabs.com. There are copycat sites popping up using similar names to piggyback off their reputation. If the URL isn’t bioedgeresearchlabs.com, it’s not them. Bookmark it.

Product-by-Product: What Paradigm Customers Were Buying

Let me run through the most popular products Paradigm used to carry and give you the straight talk on each one.

BPC-157

One of the most widely used peptides in the space. Known for gut healing, tissue repair, and injury recovery. BPC-157 has a solid research base and is one of the most reliable peptides you can run. BioEdge carries this and it’s consistently one of their top sellers.

TB-500

Often stacked with BPC-157 for a comprehensive healing protocol. TB-500 works systemically rather than locally, so it’s useful for overall recovery. The combination of BPC-157 and TB-500 is one of the most popular stacks in the peptide community for good reason.

Ostarine (MK-2866)

Paradigm’s best-selling SARM. Ostarine is popular for cutting cycles where you want to preserve lean mass while losing fat. Typical dosages ranged from 20 to 30mg daily for beginners. If you’re going to run SARMs, be aware the regulatory environment is tightening and source carefully.

LGD-4033 (Ligandrol)

Used for lean muscle gain and strength. LGD-4033 was a favorite among athletes and bodybuilders looking to add size. Like all SARMs, demand batch-specific lab results from whoever you’re buying from.

RAD-140 (Testolone)

One of the more potent SARMs, used for muscle mass and strength gains. RAD-140 has a stronger androgenic profile than Ostarine. This is not a beginner compound. If you’re going to use it, know what you’re doing and have PCT on hand.

MK-677 (Ibutamoren)

A growth hormone secretagogue, not technically a SARM. MK-677 raises GH levels through the ghrelin pathway. It’s effective but comes with side effects including water retention, increased appetite, and elevated cortisol. The regulatory outlook on MK-677 is getting worse, so keep that in mind before building a long-term protocol around it.

YK-11

A myostatin inhibitor that can promote lean muscle and strength. YK-11 is one of the more aggressive compounds in the SARM category. Typical doses range from 5 to 10mg daily. This is another one where purity is critical because you absolutely need to know what you’re actually taking.

BRL Products

Peptides can get expensive, but as an FYI - BioEdge is doing 15% off this month (code mars15 at bioedgepeptides.com), one of the few suppliers that consistently delivers what their lab reports claim.

How to Vet Any Peptide Supplier

How to vet a peptide supplier - 5 non-negotiables after the Paradigm Peptides collapse checklist infographic

The Paradigm collapse should change how you evaluate suppliers going forward. Here’s what I tell everyone in our community.

Ask for batch-specific third-party lab results. Not a general COA from a year ago. Results tied to the specific batch you’re buying, from an independent U.S. lab. If they can’t produce this, move on.

Check real community feedback. Trustpilot ratings can be gamed. Paradigm had 4.7 stars and their owner pled guilty to federal charges. Look at forums, Reddit discussions, and established peptide communities where people share actual experiences over time.

Verify shipping practices. Peptides degrade in heat. Any supplier shipping without temperature control doesn’t care about whether their product works when it arrives at your door.

Look at how they handle questions. Good suppliers welcome scrutiny. If you ask about testing, sourcing, or purity and the company gets evasive, that’s your answer.

Watch for payment processor instability. Legitimate operations maintain stable payment processing. If a company is constantly changing how they accept payments or pushing you toward crypto only, something is off behind the scenes.

Don’t Repeat the Paradigm Mistake

The biggest takeaway from Paradigm Peptides isn’t that one company was bad. It’s that you can’t afford to be passive about where you source.

Thousands of people bought from Paradigm thinking they were getting one thing and received something completely different. They made decisions about their health and their protocols based on labels that were wrong. Some of them may have experienced side effects they couldn’t explain because they didn’t know they were taking testosterone.

That’s unacceptable. And it’s preventable.

Verify everything. Source from suppliers with real, verifiable testing. Don’t trust a brand name or a website design. Trust lab results. Trust track records. Trust the companies that welcome your questions instead of hiding behind disclaimers.

If you need a place to start, BioEdge Research Labs is where I send everyone. Use code PEP10.

Stay sharp.

Joe Mars
The Peptide Report


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Disclaimer: This content is for educational and informational purposes only. It is not intended as medical advice. Peptides are sold for research purposes. Always consult with a qualified healthcare professional before starting any new protocol.

BRL Products

Peptides can get expensive, but as an FYI - BioEdge is doing 15% off this month (code mars15 at bioedgepeptides.com), one of the few suppliers that consistently delivers what their lab reports claim.

Looking for Reference-Grade Peptides?

Explore the BioEdge Research Labs catalog for verified research materials. Each batch is tested using HPLC and mass spectrometry to confirm purity and composition.

Benefits Reported In Research

● Supports recovery and tissue repair
● Aids in muscle growth and flexibility
● Helps regulate metabolism and energy use
● Encourages healthy hormone balance
● Promotes resilience under stress and inflammation

Disclaimer: Information is for educational purposes only and not a substitute for professional medical advice.

How are dosing protocols determined for research peptides?

All dosing and reconstitution protocols are developed from peer-reviewed research, preclinical data, and published studies. These frameworks exist solely for educational and laboratory use — not for human or veterinary administration. Each compound page summarizes concentration math, syringe conversions, and gradual titration examples to help researchers calculate precise microgram-level doses.

Can peptide dosing protocols be customized or adjusted?

Yes — within an educational or experimental context. Many researchers use a gradual titration approach to assess tolerance and precision, beginning at a lower dose (e.g., 150 mcg per day) and adjusting upward as needed. These models are not medical prescriptions but examples of structured research methodology.

What equipment and supplies are typically used in dosing protocols?

Common lab supplies include insulin syringes (30–100 unit), bacteriostatic water, sterile alcohol swabs, and labeled storage vials. Smaller syringes (30–50 unit) improve precision for sub-0.10 mL injections. All tools should remain sterile and disposed of properly after use to prevent contamination.

Are the dosing and protocol resources medical advice?

No. All content, including dosing charts, reconstitution instructions, and storage guidance, is for research and educational purposes only. None of this information substitutes for professional medical guidance or approval. Products referenced are intended exclusively for laboratory research use.